QUANTIFOIL is a perforated support foil with pre-defined hole size, shape and arrangement that has advantages in electron microscopy (EM) or low-energy electron point source (LEEPS) when compared with conventional holey film. QUANTIFOIL with circular holes is used in cryo-electron tomographic reconstruction. The roundness of the holes is advantageous with respect to the formation of an ice layer of constant thickness. May be preferred over R 2/2, when an increased tolerance with respect to the position of beam, and a larger beam diameter are desired, such as in the case of automated image acquisition. Hole size is 2 µm. Space between holes is 4 µm. Center to center is 6 µm. Grid: Gold. Mesh: 200 . Type: H 2 . Pitch: 127 µm.